Dehydroepiandrosterone Sulfate Treatment of Mice Modulates Infection with Schistosoma mansoni
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چکیده
منابع مشابه
Immunodiagnosis of infection with Schistosoma mansoni: Enzyme-
A circulating antigen, a negatively charged polysaccharide from the trematode Schistosoma mansoni, was noncovalently bound to the surface of poly(L-lysine).coated wells in polystyrene trays, which were then used in a micro-enzymelinked immunosorbent assay (ELISA) test. The method provides an immunodiagnostic test for schistosomiasis of exceptional sensitivity with a high degree of specificity. ...
متن کاملImmunopathology of Schistosoma mansoni infection.
Schistosomiasis mansoni is a chronic helminthic disease that affects about 100 million people in the tropics. The worms have a life span of 5 to 10 years, and they live in the mesenteric veins of the host. Lightly infected individuals are asymptomatic or manifest mild intestinal symptoms. Heavily infected individuals often develop severe morbidity with hepatosplenomegaly, sometimes with a fatal...
متن کاملCerebral vasculitis associated with Schistosoma mansoni infection
BACKGROUND Cerebral involvement in schistosomiasis is not rare, but it is underdiagnosed because of the lack of clinical suspicion and the frequency of asymptomatic forms. Neurologic complications are generally supported by granuloma formation around ectopic eggs which have migrated to the brain. Moreover, vascular lesions and cerebral arteritis have been well documented in histopathological st...
متن کاملSchistosome Syntenin Partially Protects Vaccinated Mice against Schistosoma mansoni Infection
BACKGROUND Schistosomiasis is a neglected tropical disease caused by several species of trematode of the genus Schistosoma. The disease affects more than 200 million people in the world and causes up to 280,000 deaths per year, besides having high morbidity due to chronic illness that damages internal organs. Current schistosomiasis control strategies are mainly based on chemotherapy, but many ...
متن کاملSchistosoma mansoni infection in eosinophil lineage-ablated mice.
We explore the controversial issue of the role of eosinophils in host defense against helminthic parasites using the established Schistosoma mansoni infection model in 2 novel mouse models of eosinophil lineage ablation (DeltadblGATA and TgPHIL). No eosinophils were detected in bone marrow of infected DeltadblGATA or TgPHIL mice, despite the fact that serum IL-5 levels in these infected mice ex...
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ژورنال
عنوان ژورنال: Clinical Diagnostic Laboratory Immunology
سال: 1998
ISSN: 1071-412X,1098-6588
DOI: 10.1128/cdli.5.2.251-253.1998